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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOCS7
All Species:
24.24
Human Site:
S457
Identified Species:
44.44
UniProt:
O14512
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14512
NP_055413.1
581
62969
S457
E
H
Y
R
G
T
F
S
L
W
C
H
P
K
F
Chimpanzee
Pan troglodytes
XP_512211
535
59559
K397
T
R
W
E
A
E
G
K
L
A
N
V
P
D
G
Rhesus Macaque
Macaca mulatta
XP_001082440
360
39867
T251
S
Q
G
I
T
H
H
T
R
M
E
H
Y
R
G
Dog
Lupus familis
XP_548159
411
45633
V301
F
E
D
R
C
Q
S
V
V
E
F
I
K
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHQ2
579
62765
S455
E
H
Y
R
G
T
F
S
L
W
C
H
P
K
F
Rat
Rattus norvegicus
XP_001081372
564
60962
S440
E
H
Y
R
G
T
F
S
L
W
C
H
P
K
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506079
518
56852
D393
D
G
S
F
L
V
R
D
S
S
D
D
R
Y
L
Chicken
Gallus gallus
XP_423895
264
29931
I155
D
S
S
D
P
R
Y
I
L
S
L
S
F
R
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684929
733
79803
S609
E
H
Y
R
G
T
F
S
L
W
C
H
P
K
F
Tiger Blowfish
Takifugu rubipres
NP_001116335
565
61771
S441
E
H
Y
R
G
T
F
S
L
W
C
H
P
K
F
Fruit Fly
Dros. melanogaster
NP_523390
1016
110741
S902
E
Q
D
Q
G
T
F
S
F
G
S
Y
A
K
F
Honey Bee
Apis mellifera
XP_397211
804
90105
S677
E
H
D
Q
G
N
F
S
F
G
S
C
T
K
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792866
847
94386
A478
K
S
G
F
G
D
Y
A
Q
P
E
G
S
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.6
43
69.5
N.A.
97.4
95.1
N.A.
24.1
42.6
N.A.
38.2
52.3
22
24.8
N.A.
27.8
Protein Similarity:
100
36.8
49.5
69.7
N.A.
98.1
95.8
N.A.
34.4
43.7
N.A.
48.2
62.4
32.1
39.2
N.A.
39
P-Site Identity:
100
13.3
6.6
6.6
N.A.
100
100
N.A.
0
6.6
N.A.
100
100
46.6
46.6
N.A.
6.6
P-Site Similarity:
100
20
20
20
N.A.
100
100
N.A.
6.6
26.6
N.A.
100
100
60
53.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
8
0
8
0
0
8
0
8
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
39
8
0
0
0
% C
% Asp:
16
0
24
8
0
8
0
8
0
0
8
8
0
8
0
% D
% Glu:
54
8
0
8
0
8
0
0
0
8
16
0
0
0
0
% E
% Phe:
8
0
0
16
0
0
54
0
16
0
8
0
8
0
54
% F
% Gly:
0
8
16
0
62
0
8
0
0
16
0
8
0
0
24
% G
% His:
0
47
0
0
0
8
8
0
0
0
0
47
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
8
0
0
0
8
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
8
0
0
0
0
8
54
0
% K
% Leu:
0
0
0
0
8
0
0
0
54
0
8
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
8
0
0
47
8
0
% P
% Gln:
0
16
0
16
0
8
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
8
0
47
0
8
8
0
8
0
0
0
8
24
0
% R
% Ser:
8
16
16
0
0
0
8
54
8
16
16
8
8
0
8
% S
% Thr:
8
0
0
0
8
47
0
8
0
0
0
0
8
0
0
% T
% Val:
0
0
0
0
0
8
0
8
8
0
0
8
0
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
39
0
0
0
0
0
% W
% Tyr:
0
0
39
0
0
0
16
0
0
0
0
8
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _